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Volunteers Needed for a Study of a new Injection Therapy The Department of Orthopaedics at Stony Brook University Medical Center is seeking volunteers to take part in a clinical trial to treat Dupuytren’s Contracture and fixed flexion deformity of the fingers. The condition is an abnormal thickening of tough tissue underneath the skin and palm of the fingers that can be debilitating. Some patients elect to have surgery to correct the condition. SBUMC is offering patients a non-operative treatment option.

Lawrence Hurst, M.D., Chair of Orthopaedics, and Marie Badalamente, M.D., Principal Investigator and Professor of Orthopaedics, are testing the efficacy of a new enzyme that may be able to break down the tough bands, and improve hand and finger motion for patients with the condition. The enzyme is administered via a non-operative injection.

To be eligible for the trial, participants must be 18 years of age or older, have a clinical diagnosis of Dupuytren’s Contracture and be in relatively good health. Individuals with a recent history of stroke, bleeding, and other medical conditions will not be eligible for enrollment. All participants must not have received treatment for the disorder, including surgery, within 90 days of enrollment.

According to the American Academy of Orthopaedic Surgeons, Dupuytren’s Contracture is a relatively common condition that is hereditary, appears mostly in older individuals, and occurs most frequently in Caucasians of Northern European descent. The condition has a global incidence of three-to-six percent.

SBUMC is one of numerous institutions taking part in the trial of this non-operative treatment for Dupuytren’s Contracture.

For more information about the study and enrollment, contact the Department of Orthopaedics at (631) 444-2215.
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