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SBUMC EVALUATES A DIETARY SUPPLEMENT TO IMPROVE GLUCOSE METABOLISM IN OVERWEIGHT PATIENTS WITH PRE-DIABETES:Clinical Trial of Chromium Picolinate Seeks Participants; Compensation up to $750

1/11/2008


The Department of Medicine, Division of Endocrinology, at Stony Brook University Medical Center is seeking overweight individuals who are insulin resistant to participate in a clinical trial investigating the safety and effectiveness of chromium picolinate, a dietary supplement, to improve glucose metabolism. The trial lasts two months and is sponsored by the National Institutes of Health.

Obesity often leads to insulin resistance, which is associated with the development of high cholesterol, high triglycerides, and high blood pressure, and leads to type 2 diabetes. Previous studies have shown that chromium picolinate improves insulin sensitivity in patients with type 2 diabetes.

"This study seeks to establish a treatment option for insulin resistance/glucose intolerance in overweight people prior to the transition to diabetes," says Marie C. Gelato, M.D., Ph.D., Program Director of the General Clinical Research Center (GCRC) at SBUMC and a co-investigator in the study. Dr. Gelato adds that chromium picolinate has had a wide margin of safety and may provide a therapeutic benefit without serious adverse effects.

The GCRC, which conducts the trial, is screening patients for eligibility. To participate, individuals must be 25 to 40 years of age, have a body mass index of 30 (but less than 40), be less than 300 pounds and have stable weight. Individuals who have diabetes, are pregnant, or taking dietary supplements will not be eligible.

Once found to be eligible, participants will receive either chromium picolinate or a placebo (inactive substance) for two months. Each participant will be required for numerous and follow-up visits for evaluation at the GCRC during the study period. Participants will be paid up to $750, plus transportation expenses.

For more information on eligibility criteria and to enroll in the study, call Jennifer Intravaia at the GCRC at (631) 444-3740, or Teresa Hunt-Goncalves at (631) 444-9362.

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